The Amazing Spiderman (Xbox 360, PlayStation 3, Microsoft Windows, Nintendo 3DS, Nintendo DS, Wii, iOS, Android)

The game is set after the film, where new Oscorp executive Alistair Smythe (an expert in nano-technology), plans to create more cross-species experiments using the research of Dr. Curt Connors (aka The Lizard). But the cross-species experiments escape, causing havoc in Manhattan. To combat the cross-species, which Spider-Man is one of, Alistair Smythe develops a large group of robots but winds up causing more harm to the city than good. It's now up to Spider-Man to save the city from both the cross-species experiments and robots.
               Spider-Man villains Rhino, Iguana, Felicia Hardy, Vermin and Scorpion are featured as the secondary antagonists of the game. The Lizard also has a role in the game.Alistair Smythe is the major antagonist of the game and directly responsible for everything that happens in the games and was the one who created Iguana, Rhino, Scorpion and Vermin. Developers also introduced a new piranha-like boss character created specifically for this game called Nattie.